How can I help a dog with anxiety problems stay calm when I'm not home with her?

I'm afraid the Beagle in her, alone, could well be the problem as hounds really don't do well left on their own, for long hours especially. Obviously a wire crate would perhaps be the answer, but no dog should be spending more than 4 hours in a working day crated. Perhaps having somebody come in regularly during the day might help, or getting her into a creche/dog day care centre would be a better alternative as there's also the possibility she will actually hurt herself if crated in a more solid crate. And yes, dehydration is possible.